Featuretools can be used at an enterprise level! In fact, Feature Labs, the creator of featuretools, uses it in production to solve real-world problems for businesses. Here’s a case study of how BBVA and Feature Labs worked together to use featuretools to reduce losses due to fraud.
Also, check out the article “The AI Project Manager” for how Feature Labs used featuretools in another business application to make life easier for human project managers. Finally, if you’re looking for a robust, scalable model for machine learning, read about Machine Learning 2.0 (a paradigm also developed by the Feature Labs).